nexonco-mcp
nexonco-mcp is an MCP server that exposes a tool (search_clinical_evidence) for querying and returning formatted clinical evidence from the CIViC database via flexible filters such as disease, therapy/drug, molecular profile/variant, phenotype, and evidence metadata.
Score Breakdown
⚙ Agent Friendliness
🔒 Security
The provided materials do not describe authentication/authorization, transport/security requirements for the MCP deployment, or how secrets/config are handled. As a research-focused MCP server, it should be deployed with standard infrastructure security controls (TLS, network restrictions, and secret management), but those details are not verifiable from the given README.
⚡ Reliability
Best When
Used within an MCP-capable agent environment (e.g., Claude Desktop) to support research-oriented querying and summarization over oncology variant evidence.
Avoid When
Avoid for real-time clinical decisions, regulated medical use without appropriate governance and expert oversight.
Use Cases
- • Retrieve predictive/diagnostic clinical evidence for specific cancer variants and therapies
- • Support precision oncology research workflows by searching CIViC evidence
- • Generate concise, citation-backed summaries of top evidence items for a query
Not For
- • Medical diagnosis, clinical decision-making, or treatment recommendations
- • Providing definitive clinical guidance without expert review
Interface
Authentication
No authentication mechanism is described in the provided README content for the MCP tool/server.
Pricing
No pricing or hosted service model is described; appears to be a self-hosted/open-source MCP server.
Agent Metadata
Known Gotchas
- ⚠ Only one tool is documented (search_clinical_evidence); agents may assume additional tools/operations that are not exposed.
- ⚠ The tool returns a formatted report and top-N evidence; agents needing complete datasets may need additional support not shown in README.
- ⚠ No explicit guidance is provided for handling empty results, partial matches, or backend timeouts.
Alternatives
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Scores are editorial opinions as of 2026-03-30.