{"id":"nexgene-research-nexonco-mcp","name":"nexonco-mcp","homepage":null,"repo_url":"https://github.com/Nexgene-Research/nexonco-mcp","category":"ai-ml","subcategories":[],"tags":["mcp","clinical-evidence","cancer","precision-medicine","research","civic"],"what_it_does":"nexonco-mcp is an MCP server that exposes a tool (search_clinical_evidence) for querying and returning formatted clinical evidence from the CIViC database via flexible filters such as disease, therapy/drug, molecular profile/variant, phenotype, and evidence metadata.","use_cases":["Retrieve predictive/diagnostic clinical evidence for specific cancer variants and therapies","Support precision oncology research workflows by searching CIViC evidence","Generate concise, citation-backed summaries of top evidence items for a query"],"not_for":["Medical diagnosis, clinical decision-making, or treatment recommendations","Providing definitive clinical guidance without expert review"],"best_when":"Used within an MCP-capable agent environment (e.g., Claude Desktop) to support research-oriented querying and summarization over oncology variant evidence.","avoid_when":"Avoid for real-time clinical decisions, regulated medical use without appropriate governance and expert oversight.","alternatives":["Direct CIViC database queries via CIViC web/API (if available in the same deployment context)","Other MCP servers or NANDA-linked servers that index clinical evidence data","Building a custom pipeline that queries CIViC and formats results for LLM consumption"],"af_score":51.2,"security_score":26.8,"reliability_score":31.2,"package_type":"mcp_server","discovery_source":["github"],"priority":"high","status":"evaluated","version_evaluated":null,"last_evaluated":"2026-03-30T15:18:30.074334+00:00","interface":{"has_rest_api":false,"has_graphql":false,"has_grpc":false,"has_mcp_server":true,"mcp_server_url":null,"has_sdk":false,"sdk_languages":[],"openapi_spec_url":null,"webhooks":false},"auth":{"methods":[],"oauth":false,"scopes":false,"notes":"No authentication mechanism is described in the provided README content for the MCP tool/server."},"pricing":{"model":null,"free_tier_exists":false,"free_tier_limits":null,"paid_tiers":[],"requires_credit_card":false,"estimated_workload_costs":null,"notes":"No pricing or hosted service model is described; appears to be a self-hosted/open-source MCP server."},"requirements":{"requires_signup":false,"requires_credit_card":false,"domain_verification":false,"data_residency":[],"compliance":[],"min_contract":null},"agent_readiness":{"af_score":51.2,"security_score":26.8,"reliability_score":31.2,"mcp_server_quality":62.0,"documentation_accuracy":55.0,"error_message_quality":0.0,"error_message_notes":null,"auth_complexity":85.0,"rate_limit_clarity":10.0,"tls_enforcement":20.0,"auth_strength":10.0,"scope_granularity":0.0,"dependency_hygiene":55.0,"secret_handling":60.0,"security_notes":"The provided materials do not describe authentication/authorization, transport/security requirements for the MCP deployment, or how secrets/config are handled. As a research-focused MCP server, it should be deployed with standard infrastructure security controls (TLS, network restrictions, and secret management), but those details are not verifiable from the given README.","uptime_documented":0.0,"version_stability":55.0,"breaking_changes_history":40.0,"error_recovery":30.0,"idempotency_support":"true","idempotency_notes":"The primary operation is a search/query tool; repeated calls with identical filters should be idempotent in effect, though explicit guarantees are not documented.","pagination_style":"none","retry_guidance_documented":false,"known_agent_gotchas":["Only one tool is documented (search_clinical_evidence); agents may assume additional tools/operations that are not exposed.","The tool returns a formatted report and top-N evidence; agents needing complete datasets may need additional support not shown in README.","No explicit guidance is provided for handling empty results, partial matches, or backend timeouts."]}}