Particle Health API
Particle Health provides a FHIR R4 API that aggregates patient health records from the national CommonWell and Carequality health information networks, giving AI agents access to longitudinal patient data from thousands of healthcare organizations via a single integration.
Score Breakdown
⚙ Agent Friendliness
🔒 Security
HIPAA BAA required and available. SOC2 Type II certified. CommonWell and Carequality network participation requires adherence to network-level security policies. All PHI access logged with purpose of use.
⚡ Reliability
Best When
You need broad access to patient clinical history across many healthcare organizations without building individual EHR integrations, particularly for use cases where query-on-demand retrieval is acceptable.
Avoid When
You need real-time event streaming from EHRs, write-back capability, or data from organizations not participating in CommonWell or Carequality networks.
Use Cases
- • Retrieving comprehensive longitudinal patient health records from nationwide health information networks for clinical decision support
- • Accessing historical encounter data, diagnoses, and medications prior to a patient visit for care coordination agents
- • Building risk stratification models by pulling cross-organizational clinical history for population health agents
- • Retrieving patient records for care gap identification without requiring individual health system integrations
- • Enabling prior authorization automation with complete clinical history from multiple treating organizations
Not For
- • Writing data back to EHR systems — Particle Health is read-focused; use Redox for bidirectional integration
- • Real-time ADT or event streaming — Particle is query-based, not event-driven
- • Administrative transactions like claims or eligibility — use Availity or Change Healthcare
Interface
Authentication
OAuth2 client credentials for backend service access. SMART on FHIR supported for patient-facing applications. BAA required before production access. Patient consent and purpose of use must be documented for each query under HIPAA TPO rules.
Pricing
Production access requires onboarding, BAA execution, and approval of use case. Per-patient-query pricing varies by data completeness and record volume returned.
Agent Metadata
Known Gotchas
- ⚠ Queries may return partial results if some connected health systems are temporarily unavailable — agents must handle incomplete record sets
- ⚠ BAA and purpose-of-use attestation required for every production query type — agents must pass treatment/payment/operations context with each request
- ⚠ Network query latency is higher than single-EHR APIs (often 2-10 seconds) due to federated record retrieval — agents must use async patterns
- ⚠ Patient matching uses probabilistic algorithms across organizations — duplicate or mismatched records require downstream deduplication logic
- ⚠ Data from CommonWell/Carequality reflects what member organizations have shared — coverage gaps exist for non-participating organizations
- ⚠ HIPAA minimum necessary standard applies — agents cannot retrieve full patient records without a clinical justification tied to a specific encounter or care episode
- ⚠ Sandbox synthetic data does not reflect the volume and messiness of real cross-organizational health records
Alternatives
Full Evaluation Report
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Scores are editorial opinions as of 2026-03-06.